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New ‘Langya’ virus identified in China 

China’s New Langya Virus Has Infected 35 People: At least 35 have been infected with the Langya virus in China’s Shandong and Henan provinces. What exactly is the Langya virus, and how did it come to be discovered? What are the signs and symptoms? What is its origin?


Langya Henipavirus: Almost three years after discovering the novel coronavirus in China, a new zoonotic virus has been found in the country’s two eastern provinces, with 35 infections. Langya Henipavirus, or LayV, is another name for this new type of Henipavirus.


Henipaviruses are pathogens with a biosafety level of 4 (BSL4). They can cause severe illness in animals and humans, and there are currently no licensed drugs or vaccines for humans.


What exactly is the Langya virus?


According to a recent study published in The New England Journal of Medicine titled A Zoonotic Henipavirus in Febrile Patients in China, the newly discovered virus is a “phylogenetically distinct Henipavirus.”


Before this, Henipaviruses such as Hendra, Nipah, Cedar, Mojiang, and the Ghanaian bat virus had been identified. The Cedar virus, Ghanaian bat virus, and Mojiang virus are not known to cause human disease, according to the US Centers for Disease Control and Prevention. However, Hendra and Nipah infect humans and can be fatal.


Meanwhile, Langya is known to cause fever, and the NEJM study calls for a more thorough investigation of associated human illness.


The genome organization of Langya is “identical to that of other Henipaviruses,” according to the study. It is closely related to the “Mojiang Henipavirus, which was discovered in southern China.”


How did the Langya virus get its name?

Langya became located in jap China for the duration of surveillance, trying out sufferers who had a fever in conjunction with the latest records of animal exposure. It came to be identified and isolated from the throat swab sample of one of those sufferers. The NEJM study found 35 patients with LayV infection in Shandong and Henan provinces, with 26 only infected with this new virus and no other pathogen.


Where did the Langya virus originate?


The new virus has most likely spread from an animal to humans. The RNA of the LayV virus has been found primarily in shrews, which may be its natural hosts. After conducting a serosurvey of domestic and wild animals, the researchers focused on shrews. Seropositivity was found in goats and dogs among domestic animals.


What are the Langya virus symptoms?


The study looked at 26 patients who only had LayV infection to identify the symptoms. While all 26 had fevers, 54% reported fatigue, 50% coughed, and 38% reported nausea. In addition, 35% of the total 26 reported headaches and vomiting. According to the study, 35% had impaired liver function, while 8% had impaired kidney function. The patients had “thrombocytopenia (35%), leukopenia (54%), impaired liver (35%), and kidney (8%) function,” in step with the study.


Thrombocytopenia refers to a low platelet count, whereas leukopenia refers to a decrease in white blood cell count, which reduces the body’s ability to fight disease.

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